ORGANIC ELECTRON DONORS
or the Art of Reduction
BROGGI TEAM
About Us
The BROGGI team is specialized in the study of electron donors with totally organic structures. Organic electron donors (OEDs) are reducing agents capable of spontaneous single- (SET) or double-electron transfer (DET) to organic substrates under mild and homogeneous conditions. We explore new OED structures and their reactivity as reducers. We also improve their attractiveness by designing stable latent precursors and developing unprecedented applications, such as the transformation of nucleosides or the initiation of polymerization reactions
The BROGGI team is part of the Radical Pharmaco-chemistry (PCR) group, managed by Prof. P. Vanelle (Hospital Pharmacist, specialist in anti-infectious agents). PCR’s research program is centered on the pharmacomodulation of compounds of therapeutic interest by the mean of metal catalyzed and electron transfer-assisted reactions.
The PCR group is part of the Institute of Radical Chemistry ICR, directed by Prof. Nicolas Ferré. The ICR was labelled by the french High Council for Evaluation of Research and Higher Education HCERES as a major actor in the domain of radical chemistry with teams of an excellent level of scientific production and international influences.
Team Leader
Dr. Julie Broggi – Team Leader
Associate professor, HDR at Aix Marseille University
My research focus on the synthesis and use of nitrogen-containing heterocycles with σ- and π-donor properties. During my career, I worked on σ-donor N-heterocyclic carbenes (NHC) as ligands for new organometallic complexes and use them in catalysis. Since 2012, I develop my own thematic dealing with aminoethylenes, the dimeric form of carbenes, used as organic π-electron donors (OED). I explore (1) new OED structures and (2) their reactivity as reducers. I improve their attractiveness by designing stable latent precursors and developing unprecedented applications in medicinal or polymer chemistry.
The Team
Dr. Sébastien REDON
Associate professor at Aix Marseille University
Nadhrata ASSANI
PhD student
Minh-Hang DO
M2 student
Lia PEREZ ROSTGAARD
M1 student
Amandine AVENEL
M1 student
Yara TAWK
Licence student
Publication News
α-Trifluoromethylated quinolines as safe and storable PET-donor for radical polymerizations, Macromol. Rapid Commun. 2024, 2400710
A Simple N-Heterocyclic Carbene for the Catalytic Up-conversion of Aldehydes into Stoichiometric Super Electron Donors
Chem. Sci. 2024, 15, 14699
In situ generation of n-type dopants by thermal decarboxylation
Adv. Funct. Mater. 2023, 2212305
Metal-Free SF6 Activation: A New SF5-Based Reagent Enables Deoxyfluorination and Pentafluorosulfanylation Reactions Angew. Chem. Int. Ed. 2022, 61, e202204623
Critical Assessment of the Reducing Ability of Breslow-type Derivatives and Implications for Carbene-catalyzed Radical Reactions Angew. Chem. Int. Ed. 2021, 60, 26783-26789.
Lab Tour
Fundings
We are thankful for generous funding by the following organizations:
Contact Us
Fac. de pharmacie, LPCR
27 Bd Jean Moulin
13005 Marseille
FRANCE
Webmasters : Simon Cassegrain – Julie Broggi