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Home >  Teams    > Molecular Probes and Oxidative Stress team (SMBSO)
Resp. Dr. Sylvia Pietri

Molecular Probes and Oxidative Stress team (SMBSO)
Resp. Dr. Sylvia Pietri

Objectives

Development of tools (molecules probes, processes ..) for the study of the chemical processes of living in pathologies involving oxidative stress. Synthesis of diffusible probes of intracellular pH. Synthesis of biocompatible free radical scavengers. Development of models of in vitro and in vivo studies of oxidative stress adapted to 31P NMR and in vivo RPE. Collaboration with hospital-university partners.
 

Competences

  • Organic synthesis
  • Medicinal chemistry. In vitro tests (SAR) / in vivo
  • Cell culture, animal experimentation, specialization in surgery
  • Spin-trapping / RPE and 31P NMR in vivo
  • Biochemical techniques and analytical chemistry applied to biology (chemiluminescence, spectrophotometry, HPLC ...)  

Staff

Permanent Fonction No-Permanent Statut
Sylvia Pietri DR CNRS Caroline Bonnet Post-doctorant
Marcel Culcasi CR CNRS Mathieu Cassien Post-doctorant
Anne Mercier CR CNRS Caroline Delehedde Post-doctorant
Pierre Stocker MCF AMU Emilie Ricquebourg Post-doctorant
Sophie Thétiot-Laurent MCF AMU Cherif Nader Master
Claude Arzouyan PAST

 
Address

Aix-Marseille University
Institut of Radical Chemistry, UMR 7273
SMBSO Team
Avenue Escadrille Normandie-Niemen
Case 522
13397 Marseille cedex 20
Tel: 33 (0)4 91 28 85 79

Detailed description of the SMBSO team

Scientific positioning

Multidisciplinary team, SMBSO brings together researchers specializing in synthetic chemistry, life sciences, analytical chemistry and physicochemistry, around a leading theme which is the study of the chemical processes of living in pathologies involving oxidative stress. Several complementary axes are developed in close relation:

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